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CardioFlex 510(k)
Section 7 · Substantial Equivalence
Substantial Equivalence Summary

The CardioFlex Catheter System is substantially equivalent to predicate K211045 — a steerable RF ablation catheter cleared in 2021.

Performance testing demonstrated equivalent tensile strength

Both devices are single-use, irrigated catheters classified under 21 CFR 870.3610.
2 comments · Section 14
Maya2h ago
Can we cite ASTM F2182 here? The predicate used it for flex testing.
SarahExternal45m ago
Yes — and add the 250-cycle requirement. FDA flagged this in K211045's review.
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Substantial Equivalence
3 editing now
Section 7 · paragraph 4
The subject device’s catheter shaft uses a polyurethane construction with a working length of 110 cm, identical to predicate K211045.
Performance testing followed ASTM F2182 across all benchtop conditions, demonstrating equivalent
Biocompatibility was evaluated per ISO 10993-1, with no new safety questions identified versus the predicate.
Cyclic fatigue testing followed the 250-cycle minimum from the cleared predicate’s clearance letter.
RaviQA · just now
Add the cycle-count citation here — FDA flagged this in K211045.
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CardioFlex · flex testing
Maya2h ago
Is ASTM F2182 still required for catheter flex testing if the predicate cited it?
Superagent2h ago
Yes. Both K211045 and K203312 cite F2182 with a 250-cycle minimum. Recommend matching the predicate’s exact protocol.
K211045K203312ASTM F2182
1 branch
Shared with Sarah · context intact
Sarahjust now
What did K211045’s clearance letter say about cycle-count justification?
K211045 · §6.2
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Access control — Section 14
James OkaforFull edit
Maya ChenCan suggest
Sarah Lindström (external)Comment only
Ravi ParkNo access
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Activity · Last 24h
5 events
  • JamesRA Lead
    Approved Section 14 — Performance Testing for submission
    4m ago
  • SarahExternal
    Left a comment on Indications for Use
    28m ago
  • MayaEngineer
    Edited Substantial Equivalence · 12 changes
    1h ago
  • RaviQA Reviewer
    Marked Risk Management Plan ready for review
    2h ago
  • JamesRA Lead
    Shared Section 7 with external reviewer
    3h ago
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